CLEOCIN Vaginal Ovules are used to treat infections of the vagina caused by bacteria. They should only be used by women who are not pregnant. No studies have been done to see if they are safe to use in pregnant women.

Most women found the drug easy to take. The main side effects were itching, discharge, and pain around and in the vagina. Some women got yeast infections.

CLEOCIN Vaginal Ovules are not for use in women who have an allergy to this kind of antibiotic. They should not be used for those who have had colitis or some other kinds of digestive problems.

Women who have loose stools or diarrhea after they take CLEOCIN Vaginal Ovules should contact their physician immediately.

Women who are taking CLEOCIN Vaginal Ovules should not have vaginal sex during treatment. They should not use vaginal products such as tampons or douche at this time. And they should not use latex or rubber birth control products such as condoms or vaginal contraceptive diaphragms for 3 days after treatment. CLEOCIN can weaken the latex and rubber.

Click here to view Important Safety Information for Cleocin^® Vaginal Cream (clindamycin phosphate vaginal cream).

Please see full prescribing information for Cleocin.

Adverse events related to clindamycin phosphate vaginal suppositories were reported for 10.5% of patients in clinical trials. Events reported by 1% or more of patients receiving Cleocin Vaginal Ovules included:

Urogenital System

• Vulvovaginal disorder: 3.4%
• Vaginal pain: 1.9%
• Vaginal moniliasis: 1.5%

Body as a whole

• Fungal infection: 1.0%

Other events reported by less than 1% of patients included:

Urogenital system: menstrual disorder, dysuria, pyelonephritis, vaginal discharge, and vaginitis/vaginal infection.

Body as a whole: abdominal cramps, localized abdominal pain, fever, flank pain, generalized pain, headache, localized edema, and moniliasis.

Digestive System: diarrhea, nausea, and vomiting.

Skin: nonapplication-site pruritis, rash, application-site pain, and application-site pruritis.

There may be other adverse events with Cleocin Vaginal Ovules that are not listed here. Please see full prescribing information for Cleocin.

Click here to learn about Cleocin^® Vaginal Cream (clindamycin phosphate vaginal cream).